![]() ![]() There is a correlation between the changes in RI of the umbilical artery Doppler flow and the changes in mean wall thickness of the placental vessels. When used in women at risk for a potentially compromised fetus, most trials have found that use of umbilical artery Doppler examination improves outcomes, ranging from fewer emergency deliveries to less death and serious neonatal morbidities.134-137 A key meta-analysis and a Cochrane review have shown that using umbilical artery Doppler in high. Placental tertiary-stem villi vessel-wall thickness decreases with advancing gestational age. Resistance indices were all within normal limits. There was a significant correlation between the decrease in thickness and in RI (r = 0.83, r = 0.78 in the second and third trimesters, respectively). 001) during the second trimester and 0.50micron/week (P <. The rate of decrease was 0.64micron/week (P <. Wall thickness, but not lumen size, of the tertiary-stem villi vessels decreased significantly overall at a rate of 0.63micron/week (P <. We determined vessel-wall thickness by tracing the outer and inner circumferences of digitized vessel-wall images. The monitor received microscopic images from a video camera that was mounted on a microscope. The tertiary-stem villi and their vessels were examined microscopically and assessed morphometrically using a personal computer with math co-processor and a touch-sensitive screen overlying a video monitor. Placental paraffin sections of 4-micron thickness were stained with hematoxylin and eosin and with periodic acid-Schiff reagents. ![]() The resistance index (RI) was determined from the Doppler flow velocity waveform. Each woman had undergone Doppler flow study of the umbilical artery. Placentas from 63 miscarriages and preterm and term deliveries (between 19 and 40 weeks) were used for morphometric study of the tertiary-stem villi vessels. Umbilical artery Doppler Both the ISUOG and the SMFM guidelines make recommendations in respect of monitoring FGR pregnancies and timing delivery using umbilical artery (UA) Doppler. To determine the changes in the vessel-wall thickness and the radius of the lumen in tertiary-stem villi of the placenta with advancing gestational duration and their relationship to umbilical artery Doppler flow studies. ![]()
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